Industry colleagues have been asking why our list of projects has not been updated recently. As a rule, we do not talk about current projects. We have been very fortunate that many of our clients tend to renew, and... + continue reading
Recent Portfolio
Here is a selection of true stories from the trenches: a few notable projects showcasing our recent work. With all projects, as a matter of policy we conduct knowledge transfer: we train and assist your colleagues to become experts in the maintenance of the newly built data capture workflows.
2022
Scientists at a global pharma company site here in Massachusetts used a sequence analytics toolkit that came with a business acquisition a decade ago. The original authors of the code have long moved on and eventually... + continue reading
2021
In this project we successfully set up and maintained an automated capture process for poorly formatted clinical research files incoming from offsite facilities of our client, a large US pharmaceutical company.... + continue reading
2020
In this project we helped preclinical scientists at a global pharma company site in the US establish a consistent and reproducible data workflow for post-processing assay results.
A multi-step cascade of curve... + continue reading
2019
Cheminformatics scientists at a global pharma company site here in Massachusetts have been using a lead-hopping dataset shared by the authors of a scientific article in a prestigious journal several years ago. Using... + continue reading
2019
In this project, we were hired to help our Client (a multi-site international pharma) mirror in-house in vitro assay result and annotation databases to a data warehouse for data analytics and advanced visualization.
As... + continue reading
2019
Sometimes a tried-and-true approach to solving a problem works best. In this project we were asked to automate the processing of clinical study sample shipment reports that are received from a CRO.
Our client, a global... + continue reading
2018
In this project, Saber Informatics was asked to implement a workflow management system for high-volume streams of pathology images in clinical research. Our client sends human tissue samples for analysis to partners who... + continue reading
2018
Our client (a large pharmaceutical company) works with partners who analyze tissue samples in clinical studies. Typically, more than one study would be active at a time, with multiple test panels. Raw analysis results... + continue reading
2018
Our Client (a research IT group at a midsized pharma company) was tasked with creating project dashboards for preclinical research scientists. Due to the fast-paced nature of R&D projects the dashboards needed to be... + continue reading
2017
In this project we implemented a collection of interactive data capture and analysis workflows for a DMPK team at a pharma company.
Our Client had centralized plate inventory, chemical and assay registration databases... + continue reading
2017
Tissue sample measurements submitted by multiple external partners for the same panel of clinical assays come in as tabular report files with an inconsistent file structure: layout, headers, data column names. In this... + continue reading
2017
Our Client needed to improve turnaround time for results of preclinical assays to be communicated to medicinal chemists for subsequent structure and property optimization.
Data propagation bottlenecks... + continue reading
2017
In this project we designed and implemented a control chart service for bioassay stability tracking. These charts became an invaluable everyday tool for screeners to evaluate assay performance across multiple runs.... + continue reading
2016
In the past year we have been engaged in several projects with the same requirement to make a live "status view" or "catalog" that would always contain up-to-date information about any files processed in a data flow,... + continue reading
2016
Our client reorganized some of its R&D operations and as a consequence a decision was made to divest a preclinical research facility.
Review and Register
As part of the process, historical analytical data on... + continue reading
2016
The Excel Automation component collection for Pipeline Pilot provides drag-and-drop components for reading, updating, and manipulating existing Excel files. Access any cell on a worksheet directly as you would in Excel... + continue reading
2015
Our Client in this project was a combinatorial chemistry lab in life sciences discovery research. Chemists needed a software tool to help them plan automated compound library syntheses. While there were commercial... + continue reading
2015
In this project Saber Informatics was engaged by the Client (a large pharma) to help with the tracking of clinical trial supplies. Each clinical research site that participates in an ongoing trial receives shipments... + continue reading
2015
Computational scientists at a large pharma company in Boston look for patterns in chemical and biological data related to the projects they support. They go beyond finding answers to well-defined questions and set... + continue reading
2015
Our client, a Medical Affairs department at an integrated pharma company, was in the midst of an IT system transition. Future looked bright with all the promised capabilities that the new, to-be-deployed enterprise... + continue reading
2015
Our client (a midsize scientific software company) started to outsource some of its product-related services engagements to specialized providers. An externally sourced pool of skilled software implementation... + continue reading
2015
This project is representative of the dynamic nature of pharma research informatics. Multiple commercial software tools for data capture, processing, and archival are purchased - each for its strengths - and then these... + continue reading
2015
Our Client's discovery medicinal chemistry team routinely works with computational scientists to design and optimize chemical series. Chemists requested a tool that would allow them to better prepare for design meetings... + continue reading
2014
The Client had several hundred preclinical safety studies done on rodents in the span of several years. The results (tissue gene expression data) were captured into Excel files, categorized by toxicity endpoint. Each... + continue reading
2014
The Client's scientists and laboratory technicians run experiments using instruments at multiple locations in the US and overseas. Experiment result data collected from these instruments is automatically and immediately... + continue reading
2013-2016
The free Web Design component collection for Pipeline Pilot provides drag-and-drop components for interactive data exploration and presentation. We encapsulated modern, powerful open source Web 2.0 technologies into a... + continue reading
2013-2014
An external partner (a preclinical lab services provider) runs compound safety studies for our Client on a regular basis, with more than a hundred studies per year. Each study report comes back electronically within two... + continue reading
2013-2014
In this project we developed a screening data capture web application for invitro biologists. Off-the-shelf software for data capture was not suitable in this case for reasons of existing infrastructure constraints,... + continue reading
2013
The Client's screening group needed the capability to request sample screening plates to be made from their inventory registered in ActivityBase. They wanted to be able to select plates, track their own and others'... + continue reading
2013
In a data review and visualization workflow, complex high-value kinetic assay results had to be QC-ed prior to multiparametric dose-response curve fitting and a handoff to Spotfire. The amount of cross-referenced data... + continue reading
2013
Our Client's lead optimization team uses screening data to guide synthetic steps in lead series progression. The scientists perform searches across the compound registration system, screening result database, and an... + continue reading
